Potassium antimony tartrate solution safety data sheet according to federal register vol. Sbiii and sbvcitrate complexes were separated on a prpx100 anion exchange column with 10 mmol lj1 edta1 mmol lj1 phthalic acid ph 4. Rats and rabbits exposed to antimony trioxide 90125 mg. After inhalation of antimony trioxide at an average concentration of 45 mgm 3, 23 hours daily for several weeks, guinea pigs showed interstitial pneumonitis dernehl et al. Antimonyiiid, ltartrates exhibit protonassisted enantioselective. It may also be used in the preparation of novel sbiiicontaining polyanions by reacting with trilacunary keggintype polyanions.
Potassium antimonyl tartrate 28300745 c8h4k2o12sb23h2o 667. It is speculated that antimony could be a natural cocontaminant with arsenic in some drinkingwaters gebel, 1999b. The stability constant for sbgs3 was determined to be log k 25 i 0. Material safety data sheet potassium antimony tartrate, trihydrate. Safety data sheet creation date 06aug2014 revision date 11apr2018 revision number 5 1.
Typical rough and dendritic grown morphology of silver film. The compound has long been known as a powerful emetic, and was used in the treatment of schistosomiasis and leishmaniasis. Several of its salts are used in tropical medicine as treatments for schistosomiasis. Find listings of potassium antimonyl tartrate manufacturers, antimony potassium tartrate cas no. In order to achieve reasonably high cure rates 70%, the drug had to be administered daily for up to 20 doses by means of intravenous injection with a total dose of 25 mgkg. This complex is reduced to an intensely bluecolored molybdenum blue complex by ascorbic acid. Risk of cancer for workers exposed to antimony compounds.
Antimony tartrate an overview sciencedirect topics. Antimony sodium tartrate definition of antimony sodium. The cage structure is retained in a solid that crystallizes in a cubic habit. Some antimonials such as potassium antimony tartrate have been used medicinally as parasiticides beliles, 1979. Exposure to antimony may occur via inhalation and by ingestion of contaminated food. Studies of a mixedvalence dinuclear iron polypyridyl complex. Antimony potassium tartrate apt is a complex salt that until recently was used worldwide as an antischistosomal drug. In cases where the antimony is already oxidized, it may be leached directly with hcl without the. The color is proportional to the phosphorus concentration. This complex is reduced to an intensely bluecolored complex by ascorbic acid.
Material safety data sheet potassium antimony tartrate. Antimony potassium tartrate solid is a colorless crystalline solid or a white powder. Antimony trioxide an overview sciencedirect topics. Potassium antimony tartrate c8h8ko12sb cid 56846568 structure, chemical names, physical and chemical properties, classification, patents, literature, biological. Subacute toxicity of pentavalent antimony compounds in rats. Characterization and stability of the antimonyquercetin complex. Soluble forms of antimony and arsenic tend to be quite mobile in water, whereas less soluble species. Butanedioic acid, 2,3 dihydroxy rr,r, antimony complex. Potassium antimonyiii tartrate hydrate may be used as a standard during the quantification of sb species present in the juices by hplc. Sbiii and sbvcitrate complexes were separated on a prpx100 anionexchange column with 10 mmol lj1 edta1 mmol lj1 phthalic acid ph 4.
Journal of the american chemical society 1998, 120 45, 1171411726. Following exposure to trivalent antimony tartrate, antimony is also retained in the skin, liver, skeleton, and lung in descending order. The chemical behaviour of antimony is as complex as that of arsenic, its neighbour in the periodic table wiberg, 1985. The reaction of sb203 with potassium hydrogen tartrate results in the 1. Sb 4 o 6 molecules are bicyclic cages, similar to the related oxide of phosphorusiii, phosphorus trioxide. Antimony ores are mined and then either changed to antimony metal or combined with oxygen to form antimony oxide. Leishmaniasis is a complex disease, with visceral and cutaneous manifestations, and is. Effects of antimony compounds on foetal development in rats.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Request pdf antimony potassium tartrate single source precursor, antimony potassium. It is used in textile and leather processing and as an insecticide. Antimony complexes with mannan appear to be promising for further improving. Pdf spectrometric and electrochemical investigation of. The tartrate complex does not interfere with cellular access to sbiii for uptake or extrusion 16 or with the capacity of sbiii to interact with regulatory proteins 11. Section 1 chemical product and company identification.
Interaction of antimony tartrate with the tripeptide. One day postexposure, the highest percentage of body burden is found in the gastrointestinal tract. Antimony potassium tartrate trihydrate american elements. Antimony potassium tartrate k 2 sb 2 c 4 h 4 o 6 23h 2 o, cas rn. Fowler, in handbook on the toxicology of metals fourth edition, 2015. Antimony sulfide sb 2 s 3 is mentioned in an egyptian papyrus of the 16 th century bc. Spectrometric and electrochemical investigation of vanadiumv and vanadiumiv tartrate complexes in solution. Antimony forms complex ions with organic and inorganic acids. Toxicological profile for antimony agency for toxic substances. The reliability of high voltage of the qrs complex as a diagnostic sign of left ventricular hypertrophy in adults. Identification product name antimony potassium tartrate trihydrate usp cat no. The current study infers that recognition of amino acids by antimonyiiid,ltartrate complexes requires that the chiral selector associate a. Antimony is a common urban air pollutant, occurring at an average concentration of 0.
Uses advised against food, drug, pesticide or biocidal. The black form of this pigment, which occurs naturally as the mineral stibnite, was used as mascara and known as khol. Direct experimental comparison of the theories of thermal and optical electrontransfer. Calibration curves were prepared with potassium antimonyl tartrate in 2% nitric acid. In a study on dogs, the highest antimony concentration in the lungs was measured after exposure to a particle size of 1. One ml volumetric flask for preparing the potassium dihydrogen phosphate solution. Antimony potassium tartrate request pdf researchgate. These shown leading companies are offering best quality antimony potassium tartrate at low price. Antimony is a silverywhite metal that is found in the earths crust. If breathing is difficult, remove victim to fresh air. Antimony and its inorganic compounds inhalable fraction. The sbq complex was synthetized using sbiii potassium tartrate trihydrate and quercetin anhydrous 1. The most famous user was the temptress jezebel whose exploits are. Antimony potassium tartrate hydrate american elements.
A solution of potassium antimonyiii tartrate does not react with cupric ions 6. In spite of being highly thermodynamically stable, the complex is kinetically labile. New insights into microbial oxidation of antimony and arsenic. Comparative toxicity and tissue distribution of antimony potassium. Effect of electrolyte composition on the electrodeposition. Lake study ascorbic acid method for determining phosphorous. Two 100 ml volumetric flasks for preparing dihydrogen phosphate standard and ascorbic acid. The effect of potassium antimony tartrate on coating morphology the morphology of silver electrodeposits obtained with hc electrolyte at 2. Butanedioic acid, 2,3dihydroxy rr,r, antimony complex. Interaction of antimony tartrate with the tripeptide glutathione. Inorganic antimony compounds antimony trichloride, acs reagent, acros organics cas. Antimony potassium tartrate, also known as potassium antimonyl tartrate, potassium antimontarterate, or emetic tartar, has the formula k 2 sb 2 c 4 h 2 o 6 2 and is the double salt of potassium and antimony of tartaric acid. Antimonyl potassium t recommended use laboratory chemicals.
It remains one of the largest killers in the tropical regions of america, africa and asia, with approximately 1. Antimony and its compounds were known to the ancients and there is a 5,000year old antimony vase in the louvre in paris. Oral exposure studies in syrian hamsters with an antimonytartrate complex found only minute amounts of antimony were absorbed through the gastrointestinal tract felicetti et al. A solution of potassium antimony iii tartrate does not react with cupric ions 6. Ammonium molybdate and antimony potassium tartrate react in an acid medium potassium pyrosulfate with dilute solutions of phosphorus to form a yellow colored antimonyphosphomolybdate complex. Antimony potassium tartrate manufacturers, suppliers. Distribution the distribution of antimony in the body is affected by the valence states of the particular antimony species. Silver electrodeposition from low and high concentrated. Antimony potassium tartrate trihydrate emetic tarter, potassium antimonyl tartrate, or potassium antimontarterate is a unique compound used as an emetic and for the treatment of the parasitic infections, schistosomiasis and leishmaniasis. The effects of sodium antimony tartrate on the myocardium.
A867500 synonyms antimonate2, bismutartrato4di, dipotassium, trihydrate. Health effects assessment for antimony and compounds. The current study infers that recognition of amino acids by antimonyiiid,l tartrate complexes requires that the chiral selector associate a. One 200 ml volumetric flask for preparing the potassium antimonyltartrate solution iii. Antimony in drinkingwater world health organization. Complexation effect of antimony compounds with citric acid and its. The structure of sb 2 o 3 depends on the temperature of the sample. Antimony potassium tartrate induces lipid peroxidation in cardiac myocyte cultures, which may be an explanation for the cardiotoxic effect of antimony compounds tirmenstein et al.
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